Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23508414 | 0.84 | KDM4E (0.37) | KDM4EHTTHSP90AB1 | |
| SCHEMBL23497442 | 0.82 | KDM4E (0.36) | KDM4EHTT | |
| SCHEMBL11916288 | 0.82 | KDM4E (0.36) | KDM4EHTT | |
| SCHEMBL11916287 | 0.80 | IKBKB (0.40) | KDM4E | |
| SCHEMBL18788176 | 0.66 | LMNA (0.44) | KDM4EHTT | |
| SCHEMBL23508420 | 0.64 | PDE10A (0.33) | KDM4E | |
| SCHEMBL26113070 | 0.64 | DYRK1A (0.40) | KDM4EHTT | |
| SCHEMBL26115015 | 0.64 | LMNA (0.43) | KDM4EHTT | |
| SCHEMBL23508158 | 0.63 | MAPK1 (0.30) | — | |
| SCHEMBL15719036 | 0.63 | POLB (0.41) | KDM4EHSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023135057-A1 | BICYCLIC TRIAZINE DERIVATIVES FOR THE TREATMENT OF CANCER | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2023-07-20 | — | — | WO | disclosed |