Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.49 |
| ▸ | MPC2 | O95563 | 2/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.37 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25832961 | 0.84 | PPARG (0.68) | PPARGMPC2CYP2C8CYP2C9FFAR1 | |
| SCHEMBL936483 | 0.83 | PPARG (0.72) | PPARGMPC2CYP2C8CYP2C9FFAR1 | |
| SCHEMBL19217857 | 0.81 | PPARG (0.49) | PPARGMPC2CYP2C8CYP2C9FFAR1 | |
| SCHEMBL8282070 | 0.80 | PPARG (0.47) | PPARGMPC2CYP2C8CYP2C9FFAR1 | |
| SCHEMBL24050980 | 0.79 | PPARG (0.47) | PPARGMPC2CYP2C8CYP2C9FFAR1 | |
| SCHEMBL25833062 | 0.78 | PPARG (0.54) | PPARGMPC2CYP2C8CYP2C9NPC1 | |
| SCHEMBL24212244 | 0.77 | PPARG (0.71) | PPARGMPC2CYP2C8CYP2C9FFAR1 | |
| SCHEMBL8176942 | 0.74 | HTT (0.51) | PPARGFFAR1RXRAPPARAMEN1 | |
| SCHEMBL29207071 | 0.72 | RAB9A (0.56) | NPC1RAB9AMEN1ALDH1A1MAPT | |
| SCHEMBL18541489 | 0.70 | PPARG (0.73) | PPARGMPC2CYP2C8CYP2C9FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230210825-A1 | METHODS AND COMPOSITIONS FOR TREATING SUBJECTS WITH METABOLIC DISORDERS AND CORONAVIRUS INFECTIONS | CIRIUS THERAPEUTICS, INC. | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230210825-A1 | METHODS AND COMPOSITIONS FOR TREATING SUBJECTS WITH METABOLIC DISORDERS AND CORONAVIRUS INFECTIONS | ACE, DPP4, ACE2 | PPARG 19/4885MPC2 223/4885CYP2C8 548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.