Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25468245 | 0.81 | SPHK2 (0.30) | SPHK1SPHK2 | |
| SCHEMBL3962044 | 0.75 | SPHK1 (0.38) | SPHK1SPHK2 | |
| SCHEMBL11858528 | 0.75 | SPHK1 (0.42) | SPHK1SPHK2 | |
| SCHEMBL25754404 | 0.75 | — | — | |
| SCHEMBL25754406 | 0.74 | HTT (0.32) | — | |
| SCHEMBL31086433 | 0.73 | SPHK1 (0.44) | SPHK1SPHK2 | |
| SCHEMBL10119365 | 0.73 | SPHK1 (0.44) | SPHK1SPHK2 | |
| SCHEMBL1016637 | 0.73 | — | — | |
| SCHEMBL1015468 | 0.71 | — | — | |
| SCHEMBL28382757 | 0.70 | HSD17B10 (0.52) | SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219945-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219945-A1 | IRAK DEGRADERS AND USES THEREOF | IRAK2, IRAK3, IRAK1 | SPHK1 1872/4885SPHK2 1840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.