⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25754395 | 0.89 | — | — | |
| SCHEMBL25754406 | 0.81 | HTT (0.32) | — | |
| SCHEMBL25754405 | 0.79 | CYP3A4 (0.39) | — | |
| SCHEMBL25754401 | 0.79 | — | — | |
| SCHEMBL25833279 | 0.75 | SPHK1 (0.31) | — | |
| SCHEMBL19543260 | 0.74 | ALDH1A1 (0.35) | — | |
| SCHEMBL25754410 | 0.74 | HTT (0.32) | — | |
| SCHEMBL6215601 | 0.73 | ALDH1A1 (0.32) | — | |
| SCHEMBL25754491 | 0.70 | HTT (0.32) | — | |
| SCHEMBL25754398 | 0.70 | HTT (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230210999-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) | 2023-07-06 | — | — | US | disclosed |