Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 2/20 | 0.63 |
| ▸ | ABL1 | P00519 | 3/20 | 0.56 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.55 |
| ▸ | PI4KA | P42356 | 1/20 | 0.55 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.55 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.52 |
| ▸ | PRKCG | P05129 | 2/20 | 0.52 |
| ▸ | PRKACA | P17612 | 2/20 | 0.52 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.52 |
| ▸ | AKT1 | P31749 | 2/20 | 0.52 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.52 |
| ▸ | CLK2 | P49760 | 2/20 | 0.52 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.52 |
| ▸ | PRKX | P51817 | 2/20 | 0.52 |
| ▸ | NEK4 | P51957 | 2/20 | 0.52 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.52 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.52 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.52 |
| ▸ | HIPK4 | Q8NE63 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3711380 | 0.83 | NPC1 (0.49) | PIK3CGPIK3CAPI4KAPI4KBNPC1 | |
| SCHEMBL25834501 | 0.79 | APP (0.48) | PIK3CGABL1PIK3CALIPGMAPK1 | |
| SCHEMBL27311583 | 0.79 | PIK3CG (0.67) | PIK3CGABL1PIK3CAPI4KAPI4KB | |
| SCHEMBL543954 | 0.79 | IDO1 (0.59) | CSNK1DDYRK1ANPC1MAPTRAB9A | |
| SCHEMBL1651874 | 0.77 | PIK3CG (1.00) | PIK3CGABL1PIK3CADYRK1ANPC1 | |
| SCHEMBL25464674 | 0.77 | RAB9A (0.60) | CSNK1DDYRK1ANPC1MAPTRAB9A | |
| SCHEMBL14189675 | 0.77 | NPC1 (0.61) | DYRK1ANPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL20887504 | 0.77 | PIK3CG (0.39) | PIK3CGABL1PIK3CAMAP4K4PRKCG | |
| SCHEMBL22380314 | 0.76 | ABL1 (0.66) | ABL1MAPK14 | |
| SCHEMBL25493119 | 0.76 | ABL1 (0.63) | ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131649-A1 | BENZOTHIAZOLE ANAOLOGUES AND USE THEREOF AS BOOSTERS OF ANTI TUBERCULOSIS DRUGS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2023-07-13 | — | — | WO | disclosed |