Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.71 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.67 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.60 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.49 |
| ▸ | PNMT | P11086 | 2/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3056908 | 0.83 | TAAR1 (1.00) | TAAR1AOC3SIGMAR1PYCR1PNMT | |
| SCHEMBL10294677 | 0.81 | PYCR1 (0.65) | TAAR1AOC3PYCR1PNMTALDH1A1 | |
| Hydrochloric Acid SCHEMBL8507687 | 0.81 | TAAR1 (0.96) | TAAR1AOC3SIGMAR1PYCR1PNMT | |
| SCHEMBL25852812 | 0.80 | TAAR1 (0.63) | TAAR1AOC3SIGMAR1PYCR1PNMT | |
| SCHEMBL25833563 | 0.79 | TAAR1 (0.61) | TAAR1AOC3SIGMAR1PYCR1HTR2A | |
| SCHEMBL12128216 | 0.77 | TAAR1 (0.58) | TAAR1AOC3 | |
| SCHEMBL8293202 | 0.77 | TAAR1 (0.64) | TAAR1AOC3SIGMAR1CHRM2CHRM1 | |
| SCHEMBL91272 | 0.77 | TAAR1 (0.63) | TAAR1AOC3PNMTHTR3EHTR3B | |
| SCHEMBL29848342 | 0.77 | TAAR1 (0.63) | TAAR1AOC3PNMTHTR3EHTR3B | |
| SCHEMBL11300491 | 0.76 | TAAR1 (0.79) | TAAR1AOC3SIGMAR1PYCR1PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227451-A1 | AZAINDOLE DERIVATIVES AND THEIR USE AS ERK KINASE INHIBITORS | AGV DISCOVERY (FR) | 2023-07-20 | — | — | US | disclosed |
| EP-4212531-A1 | AZAINDOLE DERIVATIVES AND THEIR USE AS ERK KINASE INHIBITORS | AGV Discovery (FR) | 2023-07-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227451-A1 | AZAINDOLE DERIVATIVES AND THEIR USE AS ERK KINASE INHIBITORS | MAPKAPK2, MAPK1, MAPK7 | TAAR1 1183/4885AOC3 3111/4885SIGMAR1 2388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.