Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.49 |
| ▸ | IDUA | P35475 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | INPPL1 | O15357 | 2/20 | 0.42 |
| ▸ | INPP5A | Q14642 | 2/20 | 0.42 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23671710 | 0.85 | SRC (0.53) | SRCIDUAPLK1INPPL1INPP5A | |
| SCHEMBL23692350 | 0.83 | SRC (0.45) | SRCIDUAPLK1INPPL1INPP5A | |
| SCHEMBL12344129 | 0.81 | SRC (0.53) | SRCPLK1INPPL1INPP5ABLM | |
| SCHEMBL269177 | 0.80 | CTBP2 (0.62) | CTBP2MMP13POLBMTNR1AMTNR1B | |
| SCHEMBL28884101 | 0.80 | SRC (0.54) | SRCIDUAPLK1INPPL1INPP5A | |
| SCHEMBL4336266 | 0.80 | SRC (0.54) | SRCIDUAPLK1INPPL1INPP5A | |
| SCHEMBL2091042 | 0.78 | CTBP2 (0.45) | CTBP2F10MMP13POLBMTNR1A | |
| SCHEMBL694402 | 0.78 | CYP3A4 (0.58) | CTBP2F10POLBLMNA | |
| SCHEMBL9162999 | 0.78 | SRC (0.53) | SRCIDUAPLK1INPPL1INPP5A | |
| SCHEMBL27826220 | 0.78 | SRC (0.53) | SRCIDUAPLK1INPPL1INPP5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209483-A1 | PRODRUG MODULATORS OF THE INTEGRATED STRESS PATHWAY | Calico Life Sciences LLC (US) | 2023-07-12 | — | — | EP | disclosed |