Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.53 |
| ▸ | INPPL1 | O15357 | 6/20 | 0.47 |
| ▸ | INPP5A | Q14642 | 5/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | IDUA | P35475 | 1/20 | 0.40 |
| ▸ | INPP5B | P32019 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | LAP3 | P28838 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.38 |
| ▸ | PPM1D | O15297 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4336266 | 0.84 | SRC (0.54) | SRCINPPL1INPP5APLK1IDUA | |
| SCHEMBL28884101 | 0.84 | SRC (0.54) | SRCINPPL1INPP5APLK1IDUA | |
| SCHEMBL12344129 | 0.82 | SRC (0.53) | SRCINPPL1INPP5APLK1BLM | |
| SCHEMBL27826220 | 0.82 | SRC (0.53) | SRCINPPL1INPP5APLK1IDUA | |
| SCHEMBL1109646 | 0.81 | CYP4F2 (0.54) | SRCINPPL1INPP5APLK1IDUA | |
| SCHEMBL130697 | 0.80 | INPPL1 (0.71) | SRCINPPL1INPP5APLK1INPP5B | |
| SCHEMBL8956803 | 0.80 | LMNA (0.40) | LMNAMAPTHTT | |
| SCHEMBL23671710 | 0.79 | SRC (0.53) | SRCINPPL1INPP5APLK1IDUA | |
| Phosphoric Acid SCHEMBL28992406 | 0.78 | INPPL1 (0.68) | SRCINPPL1INPP5APLK1INPP5B | |
| SCHEMBL25833591 | 0.78 | SRC (0.49) | SRCINPPL1INPP5APLK1IDUA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5411983-A | Certain hyrdoxy-phosphinyl-oxy-phenylmethyl-imidazolium hydroxide inner salts as PAF antagonists | AMERICAN CYANAMID COMPANY (US) | 1995-05-02 | — | — | US | disclosed |
| US-5234918-A | For cardiovascular, respiratory, carcinogenic and inflammatory disorders | AMERICAN CYANAMID COMPANY (US) | 1993-08-10 | — | — | US | disclosed |
| US-5215975-A | Certain hydroxy-phosphinyl-oxy-phenyl methyl-thiazolium hydroxide inner salts as PAF antagonists | AMERICAN CYANAMID COMPANY (US) | 1993-06-01 | — | — | US | disclosed |
| EP-0336142-A2 | Novel antagonists of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1989-10-11 | — | — | EP | disclosed |