Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 7/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2860044 | 0.88 | KDM4E (0.68) | KDM4EALDH1A1SMN1; SMN2HPGDTSHR | |
| SCHEMBL31126834 | 0.88 | KDM4E (0.68) | KDM4EALDH1A1SMN1; SMN2HPGDTSHR | |
| SCHEMBL20302610 | 0.84 | ALDH1A1 (0.54) | KDM4EALDH1A1SMN1; SMN2TSHRLMNA | |
| Diethyl Phthalate SCHEMBL5152078 | 0.82 | ALDH1A1 (0.86) | KDM4EALDH1A1SMN1; SMN2HPGDTSHR | |
| SCHEMBL1142993 | 0.82 | ALDH1A1 (0.86) | KDM4EALDH1A1SMN1; SMN2HPGDTSHR | |
| SCHEMBL14254853 | 0.81 | KDM4E (0.75) | KDM4EALDH1A1SMN1; SMN2HPGDTSHR | |
| SCHEMBL4474267 | 0.81 | CYP1A2 (0.74) | KDM4EALDH1A1SMN1; SMN2HPGDTSHR | |
| SCHEMBL3135286 | 0.81 | SMN1; SMN2 (0.82) | KDM4EALDH1A1SMN1; SMN2HPGDTSHR | |
| SCHEMBL27506182 | 0.80 | NPC1 (0.58) | KDM4EALDH1A1SMN1; SMN2HPGDTSHR | |
| SCHEMBL10501732 | 0.79 | KDM4E (0.78) | KDM4EALDH1A1SMN1; SMN2HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133524-A1 | A PROCESS FOR SYNTHESIZING KETANSERIN | TERRAN BIOSCIENCES, INC. (US) | 2023-07-13 | — | — | WO | disclosed |