Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27423623 | 0.88 | NOTUM (0.52) | EPHX2IGF1RPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL6404226 | 0.83 | EPHX1 (0.57) | EPHX2KMT2APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL27423856 | 0.82 | EPHX2 (0.49) | EPHX2SMN1; SMN2CYP1A2RAB9A | |
| SCHEMBL19263253 | 0.78 | EPHX2 (0.46) | EPHX2IGF1RPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL6403544 | 0.77 | RAB9A (0.57) | EPHX2KMT2APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL6402421 | 0.76 | RAB9A (0.59) | EPHX2KMT2APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL19263045 | 0.75 | POLB (0.46) | EPHX2KMT2AIGF1RPOLBSMN1; SMN2 | |
| SCHEMBL1096320 | 0.73 | HPGD (0.47) | EPHX2POLBSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL27422829 | 0.71 | POLB (0.57) | EPHX2IGF1RPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL27419590 | 0.71 | EPHX2 (0.67) | EPHX2KMT2APOLBSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122267-A2 | SMALL MOLECULE INHIBITORS OF MAMMALIAN SLC6A19 FUNCTION | JNANA THERAPEUTICS INC. (US) | 2023-06-29 | — | — | WO | disclosed |