Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATF4 | P18848 | 20/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19569198 | 0.94 | ATF4 (0.71) | ATF4 | |
| SCHEMBL25834026 | 0.91 | ATF4 (0.65) | ATF4 | |
| SCHEMBL25835791 | 0.89 | ATF4 (0.64) | ATF4 | |
| SCHEMBL19555251 | 0.89 | ATF4 (0.66) | ATF4 | |
| SCHEMBL19569488 | 0.89 | ATF4 (0.72) | ATF4 | |
| SCHEMBL19569580 | 0.89 | ATF4 (0.72) | ATF4 | |
| SCHEMBL19555891 | 0.88 | ATF4 (0.65) | ATF4 | |
| SCHEMBL19556275 | 0.87 | ATF4 (0.61) | ATF4 | |
| Hydrochloric Acid SCHEMBL19555276 | 0.87 | ATF4 (0.64) | ATF4 | |
| SCHEMBL22669297 | 0.87 | ATF4 (0.64) | ATF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209483-A1 | PRODRUG MODULATORS OF THE INTEGRATED STRESS PATHWAY | Calico Life Sciences LLC (US) | 2023-07-12 | — | — | EP | disclosed |