Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 9/20 | 0.66 |
| ▸ | IKZF3 | Q9UKT9 | 3/20 | 0.66 |
| ▸ | IKZF1 | Q13422 | 3/20 | 0.66 |
| ▸ | TNF | P01375 | 2/20 | 0.66 |
| ▸ | IL1B | P01584 | 2/20 | 0.66 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.66 |
| ▸ | BRD4 | O60885 | 1/20 | 0.66 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | MAP1LC3B | Q9GZQ8 | 8/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL677652 | 0.90 | CRBN (0.78) | CRBNIKZF3IKZF1TNFIL1B | |
| SCHEMBL17246851 | 0.90 | CRBN (0.78) | CRBNIKZF3IKZF1TNFIL1B | |
| SCHEMBL19359459 | 0.87 | CRBN (0.77) | CRBNIKZF3IKZF1TNFIL1B | |
| SCHEMBL19359461 | 0.87 | CRBN (0.77) | CRBNIKZF3IKZF1TNFIL1B | |
| SCHEMBL14998785 | 0.81 | CRBN (0.64) | CRBNIKZF3IKZF1TNFIL1B | |
| SCHEMBL12132407 | 0.81 | CRBN (0.58) | CRBNIKZF3IKZF1TNFIL1B | |
| SCHEMBL12132418 | 0.81 | CRBN (0.58) | CRBNIKZF3IKZF1TNFIL1B | |
| SCHEMBL12132387 | 0.81 | CRBN (0.58) | CRBNIKZF3IKZF1TNFIL1B | |
| SCHEMBL23979509 | 0.80 | CRBN (0.86) | CRBNIKZF3IKZF1TNFIL1B | |
| SCHEMBL18270884 | 0.80 | CRBN (0.86) | CRBNIKZF3IKZF1TNFIL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230226035-A1 | SMALL MOLECULES AGAINST CEREBLON TO ENHANCE EFFECTOR T CELL FUNCTION | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230226035-A1 | SMALL MOLECULES AGAINST CEREBLON TO ENHANCE EFFECTOR T CELL FUNCTION | CD4, CRBN, GZMB | CRBN 2/4885IKZF3 274/4885IKZF1 146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.