Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 12/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | DDB1 | Q16531 | 11/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31747300 | 0.81 | CRBN (0.59) | CRBNDDB1ALOX5 | |
| SCHEMBL25480083 | 0.81 | CRBN (0.55) | CRBNDDB1 | |
| SCHEMBL20909899 | 0.78 | ALOX5 (0.61) | RECQLALOX5HTR3EHTR3BHTR3A | |
| SCHEMBL36363978 | 0.74 | CRBN (1.00) | CRBNDDB1ALOX5 | |
| SCHEMBL22612095 | 0.74 | CRBN (1.00) | CRBNDDB1ALOX5 | |
| SCHEMBL22940094 | 0.74 | CRBN (0.54) | CRBNDDB1 | |
| SCHEMBL20153301 | 0.74 | RECQL (0.60) | RECQLALOX5HTR3EHTR3BHTR3A | |
| SCHEMBL22623648 | 0.73 | CRBN (0.55) | CRBNDDB1GAA | |
| SCHEMBL25026920 | 0.72 | CRBN (0.59) | CRBNDDB1ALOX5 | |
| SCHEMBL16321298 | 0.72 | RECQL (0.61) | RECQLALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125907-A1 | DEGRADATION OF BRUTON'S TYROSINE KINASE (BTK) BY CONJUGATION OF BTK INHIBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE | BEIGENE, LTD. (KY) | 2023-07-06 | — | — | WO | disclosed |