Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 6/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.36 |
| ▸ | CD44 | P16070 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.32 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.32 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.32 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.32 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.32 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.32 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.32 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29762650 | 0.78 | PNMT (0.50) | PNMTADRA2AADRA2BADRA2CHTR2C | |
| SCHEMBL21591692 | 0.78 | PNMT (0.50) | PNMTADRA2AADRA2BADRA2CHTR2C | |
| SCHEMBL20330372 | 0.78 | HTR2C (0.41) | PNMTADRA2AADRA2BADRA2CHTR2C | |
| SCHEMBL26962889 | 0.78 | HTR2C (0.41) | PNMTADRA2AADRA2BADRA2CHTR2C | |
| SCHEMBL28614325 | 0.75 | PNMT (0.53) | PNMTADRA2AADRA2BADRA2CHTR2C | |
| SCHEMBL29478566 | 0.75 | PNMT (0.53) | PNMTADRA2AADRA2BADRA2CHTR2C | |
| SCHEMBL20312856 | 0.74 | HTR2C (0.38) | PNMTADRA2AADRA2BADRA2CHTR2C | |
| SCHEMBL20883967 | 0.74 | HTR2C (0.38) | PNMTADRA2AADRA2BADRA2CHTR2C | |
| SCHEMBL30616352 | 0.74 | HTR2C (0.38) | HTR2CASIC3ADCY6ADCY3ADCY9 | |
| SCHEMBL20319254 | 0.74 | HTR2C (0.38) | HTR2CASIC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125944-A1 | COMPOUND CONTAINING HETEROCYCLIC RING | 正大天晴药业集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |