Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 10/20 | 0.69 |
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24192606 | 1.00 | DHFR (0.69) | DHFRCA1CA2CA9 | |
| SCHEMBL14417307 | 0.95 | DHFR (0.70) | DHFRCA1CA2CA9 | |
| SCHEMBL30311351 | 0.94 | DHFR (0.68) | DHFRCA1CA2CA9 | |
| SCHEMBL24344188 | 0.94 | DHFR (0.68) | DHFRCA1CA2CA9 | |
| SCHEMBL24344769 | 0.94 | DHFR (0.65) | DHFRCA1CA2CA9 | |
| SCHEMBL24192609 | 0.94 | DHFR (0.67) | DHFRCA1CA2CA9 | |
| SCHEMBL24343374 | 0.92 | DHFR (0.65) | DHFRCA1CA2CA9 | |
| SCHEMBL24193104 | 0.91 | DHFR (0.69) | DHFR | |
| SCHEMBL29027575 | 0.91 | DHFR (0.69) | DHFR | |
| SCHEMBL29027533 | 0.91 | DHFR (0.69) | DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023126297-A1 | ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES | BYONDIS B.V. (NL) | 2023-07-06 | — | — | WO | disclosed |