Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 4/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24344186 | 1.00 | DHFR (0.58) | DHFR | |
| SCHEMBL29578123 | 1.00 | DHFR (0.58) | DHFR | |
| SCHEMBL24193182 | 0.95 | DHFR (0.58) | DHFR | |
| SCHEMBL25298507 | 0.92 | DHFR (0.66) | DHFR | |
| SCHEMBL25298508 | 0.92 | DHFR (0.66) | DHFR | |
| SCHEMBL24193183 | 0.90 | DHFR (0.53) | DHFR | |
| SCHEMBL25725178 | 0.90 | DHFR (0.60) | DHFR | |
| SCHEMBL24343441 | 0.90 | DHFR (0.56) | DHFR | |
| Hydrochloric Acid SCHEMBL29579022 | 0.89 | DHFR (0.60) | DHFR | |
| SCHEMBL25725207 | 0.88 | DHFR (0.57) | DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023126297-A1 | ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES | BYONDIS B.V. (NL) | 2023-07-06 | — | — | WO | disclosed |