Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CASP1 | P29466 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.37 |
| ▸ | CDK2 | P24941 | 4/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 4/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25825961 | 0.79 | TDP1 (0.44) | ALDH1A1CYP3A4THRBALOX15TSHR | |
| SCHEMBL20631883 | 0.78 | SMN1; SMN2 (0.71) | ALDH1A1TP53HSP90AA1CYP3A4THRB | |
| SCHEMBL9255971 | 0.78 | SMN1; SMN2 (0.71) | ALDH1A1TP53HSP90AA1CYP3A4THRB | |
| SCHEMBL27766212 | 0.76 | CCNA2 (0.38) | CCNA2CDK2CCNA1CDK5DYRK1A | |
| SCHEMBL49805 | 0.74 | ALDH1A1 (1.00) | ALDH1A1TP53HSP90AA1CYP3A4THRB | |
| SCHEMBL12697232 | 0.72 | TP53 (0.61) | ALDH1A1TP53HSP90AA1CYP3A4THRB | |
| SCHEMBL2963582 | 0.71 | ALDH1A1 (0.67) | ALDH1A1TP53HSP90AA1CYP3A4THRB | |
| SCHEMBL3822625 | 0.71 | — | — | |
| SCHEMBL26045171 | 0.70 | TDP1 (0.48) | ALDH1A1TP53HSP90AA1CYP3A4THRB | |
| SCHEMBL12695048 | 0.70 | TP53 (0.59) | ALDH1A1TP53HSP90AA1CYP3A4THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | ALDH1A1 3871/4885TP53 435/4885HSP90AA1 612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.