Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.72 |
| ▸ | KIF11 | P52732 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | IDH2 | P48735 | 1/20 | 0.48 |
| ▸ | VSIR | Q9H7M9 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.47 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2807558 | 0.91 | HTT (0.69) | HTTKIF11MAPTSMN1; SMN2TP53 | |
| SCHEMBL28811027 | 0.78 | HTT (0.68) | HTTKIF11MAPTTP53KMT2A | |
| SCHEMBL3439833 | 0.76 | HTT (0.64) | HTTKIF11KMT2AMEN1ALDH1A1 | |
| SCHEMBL19645433 | 0.72 | HTT (0.60) | HTTKIF11MAPTSMN1; SMN2KMT2A | |
| SCHEMBL30822911 | 0.71 | HTT (0.58) | HTTKIF11MAPTIDH2LMNA | |
| SCHEMBL12484958 | 0.71 | MAPT (0.65) | HTTMAPTSMN1; SMN2TP53KMT2A | |
| SCHEMBL30822932 | 0.70 | DYRK1A (0.67) | HTTKIF11IDH2 | |
| SCHEMBL1998475 | 0.70 | AKR1C3 (0.59) | HTTKIF11KMT2AMEN1IDH2 | |
| SCHEMBL16029645 | 0.70 | ADORA2A (0.72) | HTTMAPTSMN1; SMN2KMT2ATAAR1 | |
| SCHEMBL8537131 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023120452-A1 | SREBP-1 INHIBITOR AND PHARMACEUTICAL COMPOSITION FOR TREATING HYPERTRIGLYCERIDEMIA | 国立大学法人筑波大学 | 2023-06-29 | — | — | WO | disclosed |