Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.57 |
| ▸ | NPC1 | O15118 | 7/20 | 0.57 |
| ▸ | RAB9A | P51151 | 7/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.57 |
| ▸ | RELA | Q04206 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38249 | 0.80 | CNR2 (0.48) | MAPTNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL38629 | 0.73 | MAPT (0.74) | MAPTNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL31009701 | 0.70 | SYK (0.44) | MAPTNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL29314089 | 0.69 | SYK (0.43) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL31009965 | 0.69 | SYK (0.43) | MAPTNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL31009973 | 0.69 | KDM4E (0.39) | MAPTNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL31009714 | 0.68 | SYK (0.42) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL8605585 | 0.66 | ALDH1A1 (0.53) | MAPTSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL11142367 | 0.66 | ALDH1A1 (0.74) | NPC1RAB9ASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL31296338 | 0.66 | ALDH1A1 (0.56) | NPC1RAB9ASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023120452-A1 | SREBP-1 INHIBITOR AND PHARMACEUTICAL COMPOSITION FOR TREATING HYPERTRIGLYCERIDEMIA | 国立大学法人筑波大学 | 2023-06-29 | — | — | WO | disclosed |