SCHEMBL25835592

SCHEMBL25835592

Cc1ccc(C(OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)OCC2c3ccccc3-c3ccccc32)(c2ccccc2)c2ccccc2Cl)cc1

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.44
FABP7 O15540 1/20 0.36
FABP5 Q01469 1/20 0.36
MDM2 Q00987 1/20 0.34
MDM4 O15151 1/20 0.33
TP53 P04637 1/20 0.33
LMNA P02545 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TLR2 O60603 2/20 0.33
EPHX2 P34913 1/20 0.33
CASP3 P42574 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17751582 1.00 KMT2A (0.44) KMT2AFABP7FABP5MDM2MDM4
SCHEMBL18177182 0.99 KMT2A (0.44) KMT2AFABP7FABP5MDM2MDM4
SCHEMBL25657687 0.92 KMT2A (0.48) KMT2AFABP7FABP5MDM2MDM4
SCHEMBL17751637 0.89 KMT2A (0.56) KMT2AFABP7FABP5MDM2MDM4
SCHEMBL17751714 0.89 KMT2A (0.56) KMT2AFABP7FABP5MDM2MDM4
SCHEMBL17751719 0.89 KMT2A (0.56) KMT2AFABP7FABP5MDM2MDM4
SCHEMBL13254138 0.89 KMT2A (0.56) KMT2AFABP7FABP5MDM2MDM4
SCHEMBL17751718 0.89 KMT2A (0.56) KMT2AFABP7FABP5MDM2MDM4
SCHEMBL17751724 0.89 KMT2A (0.56) KMT2AFABP7FABP5MDM2MDM4
SCHEMBL17751716 0.89 KMT2A (0.56) KMT2AFABP7FABP5MDM2MDM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS Arrowhead Pharmaceuticals, Inc. 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS CPT1B, MUSK, MYLK2 KMT2A 1603/4885FABP7 100/4885FABP5 304/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.