Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CCR1 | P32246 | 2/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10392770 | 0.80 | KDM4E (0.42) | ALDH1A1KDM4EHPGDHSD17B10USP2 | |
| SCHEMBL12809079 | 0.78 | KDM4E (0.50) | ALDH1A1KDM4EHPGDHSD17B10USP2 | |
| SCHEMBL7127321 | 0.77 | KDM4E (0.46) | ALDH1A1KDM4EHPGDHSD17B10USP2 | |
| SCHEMBL20038562 | 0.75 | KDM4E (0.38) | ALDH1A1KDM4EHPGDHSD17B10USP2 | |
| SCHEMBL10025403 | 0.74 | KCNH2 (0.46) | ALDH1A1KDM4EHSD17B10KMT2A | |
| SCHEMBL22853883 | 0.73 | KDM4E (0.65) | ALDH1A1KDM4EHPGDHSD17B10USP2 | |
| SCHEMBL17433348 | 0.73 | KDM4E (0.43) | ALDH1A1KDM4EHPGDHSD17B10USP2 | |
| SCHEMBL929424 | 0.73 | KDM4E (0.43) | ALDH1A1KDM4EHPGDHSD17B10USP2 | |
| SCHEMBL18806278 | 0.73 | KDM4E (0.43) | ALDH1A1KDM4EHPGDHSD17B10USP2 | |
| SCHEMBL29672807 | 0.73 | KDM4E (0.65) | ALDH1A1KDM4EHPGDHSD17B10USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125944-A1 | COMPOUND CONTAINING HETEROCYCLIC RING | 正大天晴药业集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |