SCHEMBL10025403

SCHEMBL10025403

CCCCCCc1nc(C)ccc1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.46
DHFR P00374 1/20 0.40
GCGR P47871 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
KDM4E B2RXH2 2/20 0.37
ALDH1A1 P00352 2/20 0.37
ESR1 P03372 2/20 0.37
ADRA2A P08913 2/20 0.37
ADORA3 P0DMS8 2/20 0.37
TACR2 P21452 2/20 0.37
SLC6A2 P23975 2/20 0.37
SLC6A4 P31645 2/20 0.37
SLC6A3 Q01959 2/20 0.37
LMNA P02545 1/20 0.37
SHBG P04278 1/20 0.37
TP53 P04637 1/20 0.37
CYP3A4 P08684 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19966840 0.81 KCNH2 (0.43) KCNH2DHFRGCGRMEN1KMT2A
SCHEMBL25813436 0.81 KDM4E (0.37) KMT2AKDM4EALDH1A1HSD17B10
SCHEMBL26681122 0.79 KCNH2 (0.40) KCNH2DHFRGCGRMEN1KMT2A
SCHEMBL7127321 0.77 KDM4E (0.46) MEN1KMT2ATDP1L3MBTL1KDM4E
SCHEMBL22335907 0.76 MEN1 (0.49) MEN1KMT2ATDP1L3MBTL1KDM4E
SCHEMBL25835676 0.74 ALDH1A1 (0.41) KMT2AKDM4EALDH1A1HSD17B10
SCHEMBL12809079 0.74 KDM4E (0.50) KMT2AKDM4EALDH1A1HSD17B10ADORA2A
SCHEMBL12900212 0.73 GABRP (0.58) DHFRKDM4ELMNATP53
SCHEMBL27813430 0.73 TYR (0.47) KCNH2MEN1KMT2ATDP1KDM4E
SCHEMBL28750605 0.72 PTGS2 (0.46) KCNH2KDM4EALDH1A1ESR1ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8384286-B2 Compound and organic light emitting device using the compound CANON KABUSHIKI KAISHA (JP) 2013-02-26 US disclosed
US-8318321-B2 Compound and organic light-emitting device CANON KABUSHIKI KAISHA (JP) 2012-11-27 US disclosed
US-8288016-B2 Fused polycyclic compound and organic light-emitting device using the compound CANON KABUSHIKI KAISHA (JP) 2012-10-16 US disclosed
US-8263235-B2 High light extraction efficiency and good in an light emitting efficiency and durability CANON KABUSHIKI KAISHA (JP) 2012-09-11 US disclosed
US-20120043535-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE COMPOUND CANON KABUSHIKI KAISHA (JP) 2012-02-23 US disclosed
US-8072136-B2 Compound and organic light emitting device using the compound CANON KABUSHIKI KAISHA (JP) 2011-12-06 US disclosed
US-7981525-B2 Naphthalene compound and organic light-emitting device using the compound CANON KABUSHIKI KAISHA (JP) 2011-07-19 US disclosed
US-7982213-B2 Phenanthroline compound and organic light emitting device using same CANON KABUSHIKI KAISHA (JP) 2011-07-19 US disclosed
US-20110127908-A1 FUSED POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING THE COMPOUND CANON KABUSHIKI KAISHA (JP) 2011-06-02 US disclosed
US-7923129-B2 extremely high efficiency and a high luminance and has an extremely high durability; 2-pyrenylcarbazoles; blue CANON KABUSHIKI KAISHA (JP) 2011-04-12 US disclosed
US-20090004507-A1 ORGANIC LIGHT EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2009-01-01 US disclosed
US-20080224603-A1 NAPHTHALENE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING THE COMPOUND CANON KABUSHIKI KAISHA (JP) 2008-09-18 US disclosed
US-7387845-B2 Monoamino compound and organic luminescence device using the same CANON KABUSHIKI KAISHA (JP) 2008-06-17 US disclosed
US-20080138656-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2008-06-12 US disclosed
US-20080131731-A1 CARBAZOLE DERIVATIVE AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2008-06-05 US disclosed
US-20080119671-A1 PYRENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2008-05-22 US disclosed
US-7338721-B2 Condensed polycyclic compound and organic light-emitting device using the same CANON KABUSHIKI KAISHA (JP) 2008-03-04 US disclosed
US-7241513-B2 Fluorene compound and organic luminescent device using the same CANON KABUSHIKI KAISHA (JP) 2007-07-10 US disclosed
US-7232618-B2 Organic light-emitting device CANON KABUSHIKI KAISHA (JP) 2007-06-19 US disclosed
US-7229702-B2 Oligofluorenlylene compounds CANON KABUSHIKI KAISHA (JP) 2007-06-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080224603-A1 NAPHTHALENE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING THE COMPOUND AHR, CRY1, NR2E3 KCNH2 455/4885DHFR 2884/4885GCGR 2018/4885
US-20080131731-A1 CARBAZOLE DERIVATIVE AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME OXA1L, CYP2C19, PPOX KCNH2 414/4885DHFR 3315/4885GCGR 1934/4885
US-20080119671-A1 PYRENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE AHR, CYP1A1, ARNT KCNH2 1798/4885DHFR 2083/4885GCGR 1387/4885
US-20110127908-A1 FUSED POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING THE COMPOUND RPS19, RPL19, RNF168 KCNH2 42/4885DHFR 3037/4885GCGR 1996/4885
US-20080138656-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CRY1, ORC3, OXER1 KCNH2 478/4885DHFR 3676/4885GCGR 1244/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.