SCHEMBL25835728

SCHEMBL25835728

CCCCCCCCCCCCCCCC(=O)NCCOCCNC(=O)CCOCCNC(=O)CC[C@H](NC(=O)CCOCCN=[N+]=[N-])C(=O)NCCOCCC(=O)NCCOCCNC(=O)CCCCCCCCCCCCCCC

nearest known ligand 0.59

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.59
▸ LPAR3 Q9UBY5 4/20 0.46
▸ LPAR1 Q92633 3/20 0.45
▸ NOD1 Q9Y239 4/20 0.43
▸ TLR2 O60603 2/20 0.42
▸ ENPP2 Q13822 1/20 0.38
▸ LPAR2 Q9HBW0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16710906 0.89 GLP1R (0.63) GLP1RNOD1
SCHEMBL25431848 0.85 GLP1R (0.46) GLP1R
SCHEMBL25431845 0.85 GLP1R (0.46) GLP1R
SCHEMBL26031849 0.85 LPAR1 (0.49) GLP1RLPAR1ENPP2LPAR2
SCHEMBL30571242 0.85 GLP1R (0.43) GLP1R
SCHEMBL17480732 0.84 LPAR1 (0.48) GLP1RLPAR1ENPP2LPAR2
SCHEMBL17481272 0.84 LPAR1 (0.48) GLP1RLPAR1ENPP2LPAR2
SCHEMBL17480750 0.84 LPAR1 (0.48) GLP1RLPAR1ENPP2LPAR2
SCHEMBL26032382 0.84 LPAR1 (0.48) GLP1RLPAR1ENPP2LPAR2
SCHEMBL27243701 0.84 LPAR1 (0.48) GLP1RLPAR1ENPP2LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS Arrowhead Pharmaceuticals, Inc. 2023-07-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS CPT1B, MUSK, MYLK2 GLP1R 1985/4885LPAR3 153/4885LPAR1 147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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