Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 20/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.47 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25300718 | 0.90 | AVPR1A (0.56) | AVPR1AKCNH2AVPR2 | |
| SCHEMBL25300717 | 0.90 | AVPR1A (0.56) | AVPR1AKCNH2AVPR2 | |
| SCHEMBL25835837 | 0.89 | AVPR1A (0.57) | AVPR1AKCNH2AVPR2 | |
| SCHEMBL25835821 | 0.88 | AVPR1A (0.50) | AVPR1AKCNH2AVPR2 | |
| SCHEMBL25835716 | 0.86 | AVPR1A (0.53) | AVPR1AKCNH2AVPR2 | |
| SCHEMBL25837204 | 0.84 | AVPR1A (0.48) | AVPR1AKCNH2AVPR2 | |
| SCHEMBL25835870 | 0.84 | AVPR1A (0.48) | AVPR1AKCNH2AVPR2 | |
| SCHEMBL25837198 | 0.82 | AVPR1A (0.50) | AVPR1AKCNH2AVPR2 | |
| SCHEMBL25225759 | 0.80 | AVPR1A (0.58) | AVPR1AKCNH2AVPR2 | |
| SCHEMBL25263279 | 0.80 | AVPR1A (0.58) | AVPR1AKCNH2AVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230202990-A1 | CYCLOHEXYL SUBSTITUTED TRIAZOLES | HOFFMANN-LA ROCHE INC. (US) | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230202990-A1 | CYCLOHEXYL SUBSTITUTED TRIAZOLES | AVPR1A, AVPR1B, AVPR2 | AVPR1A 1/4885KCNH2 2524/4885AVPR2 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.