SCHEMBL25836206

SCHEMBL25836206

O=c1[nH]c2cc3c(cc2c2cc4[nH]c5ccc(-n6c7ccccc7c7ccccc76)cc5c4cc12)[nH]c1ccc(-n2c4ccccc4c4ccccc42)cc13

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 5/20 0.43
AHR P35869 1/20 0.42
KDM4E B2RXH2 2/20 0.40
MEN1 O00255 1/20 0.40
TNKS O95271 1/20 0.40
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
CYP1A2 P05177 1/20 0.40
GPR3 P46089 1/20 0.40
BLM P54132 1/20 0.40
PMP22 Q01453 1/20 0.40
KMT2A Q03164 1/20 0.40
PARP15 Q460N3 1/20 0.40
HSD17B10 Q99714 1/20 0.40
TNKS2 Q9H2K2 1/20 0.40
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
SRC P12931 1/20 0.38
ADORA3 P0DMS8 5/20 0.38
CASP7 P55210 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25836209 0.91 AHR (0.37) PARP1AHRKDM4EMEN1TNKS
SCHEMBL25837026 0.90 PARP1 (0.44) PARP1AHRKDM4EMEN1TNKS
SCHEMBL12811233 0.88 AHR (0.53) AHRKDM4EMEN1ALDH1A1LMNA
SCHEMBL14039141 0.87 KDM4E (0.47) AHRKDM4EMEN1ALDH1A1LMNA
SCHEMBL14052105 0.85 AHR (0.60) AHRKDM4EMEN1ALDH1A1GPR3
SCHEMBL45708 0.85 KDM4E (0.52) PARP1AHRKDM4EMEN1ALDH1A1
SCHEMBL29354460 0.85 KDM4E (0.52) PARP1AHRKDM4EMEN1ALDH1A1
SCHEMBL25836579 0.84 KDM4E (0.45) PARP1AHRKDM4EMEN1TNKS
SCHEMBL12811694 0.84 AHR (0.53) AHRKDM4EMEN1ALDH1A1GPR3
SCHEMBL25836442 0.83 KDM4E (0.50) PARP1KDM4EMEN1TNKSALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023110742-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-06-22 WO disclosed