SCHEMBL25836209

SCHEMBL25836209

O=c1[nH]c2c(ccc3c4cc(-n5c6ccccc6c6ccccc65)ccc4[nH]c32)c2cc3[nH]c4ccc(-n5c6ccccc6c6ccccc65)cc4c3cc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 1/20 0.37
PARP1 P09874 5/20 0.36
GABRP O00591 1/20 0.35
GABRD O14764 1/20 0.35
GABRA1 P14867 1/20 0.35
GABRB1 P18505 1/20 0.35
GABRG2 P18507 1/20 0.35
GABRB3 P28472 1/20 0.35
GABRA5 P31644 1/20 0.35
GABRA3 P34903 1/20 0.35
GABRA2 P47869 1/20 0.35
GABRB2 P47870 1/20 0.35
GABRA4 P48169 1/20 0.35
GABRE P78334 1/20 0.35
GABRA6 Q16445 1/20 0.35
GABRG1 Q8N1C3 1/20 0.35
GABRG3 Q99928 1/20 0.35
GABRQ Q9UN88 1/20 0.35
KDM4E B2RXH2 4/20 0.34
ATM Q13315 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25836206 0.91 PARP1 (0.43) AHRPARP1KDM4EATML3MBTL1
SCHEMBL25837026 0.84 PARP1 (0.44) AHRPARP1KDM4ETP53ALDH1A1
SCHEMBL12811233 0.83 AHR (0.53) AHRKDM4EATML3MBTL1TP53
SCHEMBL25836121 0.81 AHR (0.58) AHRPARP1GABRPGABRDGABRA1
SCHEMBL25836018 0.81 AHR (0.58) AHRPARP1GABRPGABRDGABRA1
SCHEMBL14039141 0.81 KDM4E (0.47) AHRKDM4EATML3MBTL1TP53
SCHEMBL22514639 0.80 AHR (0.50) AHRGABRPGABRDGABRA1GABRB1
SCHEMBL14052105 0.80 AHR (0.60) AHRKDM4EATML3MBTL1TP53
SCHEMBL45708 0.80 KDM4E (0.52) AHRPARP1GABRPGABRDGABRA1
SCHEMBL29354460 0.80 KDM4E (0.52) AHRPARP1GABRPGABRDGABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023110742-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-06-22 WO disclosed