Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 15/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PKLR | P30613 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26647348 | 0.82 | NPC1 (0.48) | HPGDLRRK2 | |
| SCHEMBL30828960 | 0.82 | NPC1 (0.48) | HPGDLRRK2 | |
| SCHEMBL21500077 | 0.74 | ROCK2 (0.40) | CNR2SCN9A | |
| SCHEMBL15652305 | 0.73 | KDM4E (0.51) | HPGDGAALRRK2 | |
| SCHEMBL15962052 | 0.71 | KDM4E (0.51) | — | |
| SCHEMBL4651223 | 0.70 | MAPK1 (0.43) | HPGDGAA | |
| SCHEMBL31512136 | 0.70 | MAPK1 (0.43) | HPGDGAA | |
| SCHEMBL20254519 | 0.69 | TDP1 (0.61) | — | |
| SCHEMBL21961311 | 0.68 | NR2E1 (0.39) | SCN9AHPGD | |
| SCHEMBL20918860 | 0.67 | KDM4A (0.39) | CNR2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023137356-A1 | 15-PGDH INHIBITORS | VENTYX BIOSCIENCES, INC. (US) | 2023-07-20 | — | — | WO | disclosed |