Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 18/20 | 0.77 |
| ▸ | DHFR | P00374 | 2/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31326972 | 1.00 | DHODH (0.77) | DHODHDHFRNR4A2 | |
| SCHEMBL25837167 | 0.91 | DHODH (0.77) | DHODHDHFRNR4A2 | |
| SCHEMBL31326971 | 0.91 | DHODH (0.77) | DHODHDHFRNR4A2 | |
| SCHEMBL25839308 | 0.88 | DHODH (0.83) | DHODHDHFRNR4A2 | |
| SCHEMBL31326983 | 0.88 | DHODH (0.83) | DHODHDHFRNR4A2 | |
| SCHEMBL517489 | 0.87 | DHODH (1.00) | DHODHDHFRNR4A2 | |
| SCHEMBL25839326 | 0.87 | DHODH (0.80) | DHODHDHFRNR4A2 | |
| SCHEMBL25839019 | 0.84 | DHODH (0.76) | DHODHDHFRNR4A2 | |
| SCHEMBL31026697 | 0.83 | DHODH (0.77) | DHODHDHFRNR4A2 | |
| SCHEMBL25839318 | 0.83 | DHODH (0.77) | DHODHDHFRNR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023118576-A1 | DHODH INHIBITORS CONTAINING A CARBOXYLIC ACID BIOISOSTERE | IMMUNIC AG (DE) | 2023-06-29 | — | — | WO | disclosed |