Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 18/20 | 0.77 |
| ▸ | DHFR | P00374 | 2/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25839318 | 1.00 | DHODH (0.77) | DHODHDHFRNR4A2 | |
| SCHEMBL517489 | 0.87 | DHODH (1.00) | DHODHDHFRNR4A2 | |
| SCHEMBL31326983 | 0.86 | DHODH (0.83) | DHODHDHFRNR4A2 | |
| SCHEMBL25839308 | 0.86 | DHODH (0.83) | DHODHDHFRNR4A2 | |
| SCHEMBL25839326 | 0.84 | DHODH (0.80) | DHODHDHFRNR4A2 | |
| SCHEMBL31326971 | 0.83 | DHODH (0.77) | DHODHDHFRNR4A2 | |
| SCHEMBL31326972 | 0.83 | DHODH (0.77) | DHODHDHFRNR4A2 | |
| SCHEMBL25837167 | 0.83 | DHODH (0.77) | DHODHDHFRNR4A2 | |
| SCHEMBL25837168 | 0.83 | DHODH (0.77) | DHODHDHFRNR4A2 | |
| SCHEMBL25838915 | 0.82 | DHODH (0.76) | DHODHDHFRNR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250066290-A1 | DHODH INHIBITORS CONTAINING A CARBOXYLIC ACID BIOISOSTERE | IMMUNIC AG (DE) | 2025-02-27 | — | — | US | disclosed |
| CN-118382610-A | DHODH inhibitors containing carboxylic acid bioisosteres | 埃慕尼克股份公司 | 2024-07-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250066290-A1 | DHODH INHIBITORS CONTAINING A CARBOXYLIC ACID BIOISOSTERE | DHODH, DBH, DOHH | DHODH 1/4885DHFR 47/4885NR4A2 2440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.