SCHEMBL25837274

SCHEMBL25837274

CCN1/C(=C/C=C2\CCC(/C=C/C3=[N+](CC)c4ccc(C(=O)OCCCOC)cc4C3(C)C)=C2N(c2ccccc2)c2ccccc2)C(C)(C)c2cc(C(=O)OCCCOC)ccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.38
LMNA P02545 3/20 0.38
RAB9A P51151 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
MEN1 O00255 2/20 0.38
POLB P06746 2/20 0.38
MAPT P10636 2/20 0.38
ALPG P10696 2/20 0.38
THRB P10828 2/20 0.38
PKM P14618 2/20 0.38
XBP1 P17861 2/20 0.38
HTT P42858 2/20 0.38
KMT2A Q03164 2/20 0.38
USP2 O75604 1/20 0.38
S1PR2 O95136 1/20 0.38
CRHBP P24387 1/20 0.38
RECQL P46063 1/20 0.38
BLM P54132 1/20 0.38
CRHR2 Q13324 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL860217 0.96 MEN1 (0.39) NPC1LMNARAB9ASMN1; SMN2MEN1
SCHEMBL859631 0.92 MEN1 (0.41) NPC1LMNARAB9ASMN1; SMN2MEN1
SCHEMBL859647 0.89 HTT (0.39) NPC1LMNARAB9ASMN1; SMN2MEN1
SCHEMBL860073 0.89 MEN1 (0.43) NPC1LMNARAB9ASMN1; SMN2MEN1
SCHEMBL859829 0.87 MEN1 (0.42) NPC1LMNARAB9ASMN1; SMN2MEN1
SCHEMBL25837272 0.86 PRMT1 (0.43) NPC1LMNARAB9ASMN1; SMN2MEN1
SCHEMBL25837277 0.86 MAPT (0.39) NPC1LMNARAB9ASMN1; SMN2MEN1
SCHEMBL14198664 0.85 MEN1 (0.41) NPC1LMNARAB9ASMN1; SMN2MEN1
SCHEMBL860362 0.84 MEN1 (0.39) NPC1LMNARAB9ASMN1; SMN2MEN1
SCHEMBL12154989 0.84 MEN1 (0.44) NPC1LMNARAB9ASMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230226814-A1 ON-PRESS DEVELOPMENT TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE, AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed
US-20230219336-A1 ON-PRESS DEVELOPMENT TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE, AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2023-07-13 US disclosed
US-20230127702-A1 ON-PRESS DEVELOPMENT TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE, AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2023-04-27 US disclosed