SCHEMBL860362

SCHEMBL860362

CCN1/C(=C/C=C2\CCC(/C=C/C3=[N+](CC)c4ccc(OC(=O)COCCOC)cc4C3(C)C)=C2N(c2ccccc2)c2ccccc2)C(C)(C)c2cc(OC(=O)COCCOC)ccc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.39
NPC1 O15118 1/20 0.39
USP2 O75604 1/20 0.39
S1PR2 O95136 1/20 0.39
LMNA P02545 1/20 0.39
POLB P06746 1/20 0.39
MAPT P10636 1/20 0.39
ALPG P10696 1/20 0.39
THRB P10828 1/20 0.39
PKM P14618 1/20 0.39
XBP1 P17861 1/20 0.39
CRHBP P24387 1/20 0.39
HTT P42858 1/20 0.39
RECQL P46063 1/20 0.39
RAB9A P51151 1/20 0.39
BLM P54132 1/20 0.39
KMT2A Q03164 1/20 0.39
CRHR2 Q13324 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14573276 0.90 MEN1 (0.40) MEN1NPC1USP2S1PR2LMNA
SCHEMBL14198664 0.90 MEN1 (0.41) MEN1NPC1USP2S1PR2LMNA
SCHEMBL12154989 0.87 MEN1 (0.44) MEN1NPC1USP2S1PR2LMNA
SCHEMBL860217 0.87 MEN1 (0.39) MEN1NPC1USP2S1PR2LMNA
SCHEMBL859647 0.85 HTT (0.39) MEN1NPC1USP2S1PR2LMNA
SCHEMBL859631 0.84 MEN1 (0.41) MEN1NPC1USP2S1PR2LMNA
SCHEMBL25837274 0.84 NPC1 (0.38) MEN1NPC1USP2S1PR2LMNA
SCHEMBL860073 0.84 MEN1 (0.43) MEN1NPC1USP2S1PR2LMNA
SCHEMBL860213 0.84 MEN1 (0.47) MEN1NPC1USP2S1PR2LMNA
SCHEMBL859829 0.83 MEN1 (0.42) MEN1NPC1USP2S1PR2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8142983-B2 Lithographic printing plate precursor and method of lithographic printing FUJIFILM CORPORATION (JP) 2012-03-27 US disclosed
US-20090233229-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING FUJIFILM CORPORATION (JP) 2009-09-17 US disclosed
US-20080096132-A1 mixing a polymerizable monomer in which acrylonitrile accounts for 70% by weight or more of a total of the polymerizable monomer, water and an alkali metal persulfate polymerization initiator to conduct emulsion polymerization; distilling off unpolymerized monomers; chemical resistance film, gas barrier FUJIFILM CORPORATION 2008-04-24 US disclosed
US-20080087183-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2008-04-17 US disclosed
US-20070056457-A1 Lithographic printing plate precursor, lithographic printing method, and novel cyanine dye FUJI PHOTO FILM CO., LTD. 2007-03-15 US disclosed
US-20070056457-A1 Lithographic printing plate precursor, lithographic printing method, and novel cyanine dye FUJI PHOTO FILM CO., LTD. 2007-03-15 US disclosed