Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23997578 | 0.84 | MEN1 (0.40) | TDP1MAOAMAOBKMT2AMEN1 | |
| SCHEMBL20782862 | 0.81 | TDP1 (0.43) | TDP1MAOAMAOBKMT2AMEN1 | |
| SCHEMBL19654856 | 0.80 | TDP1 (0.40) | TDP1MAOAMAOBKMT2AMEN1 | |
| SCHEMBL12801496 | 0.78 | TDP1 (0.41) | TDP1MAOAMAOBKMT2AMEN1 | |
| SCHEMBL8295860 | 0.77 | MAOA (0.51) | TDP1MAOAMAOBKMT2AMEN1 | |
| SCHEMBL21687230 | 0.77 | TDP1 (0.40) | TDP1MAOAMAOBKMT2AMEN1 | |
| SCHEMBL18689367 | 0.76 | TDP1 (0.48) | TDP1MAOAMAOBKMT2AMEN1 | |
| SCHEMBL19407027 | 0.75 | TDP1 (0.39) | TDP1MAOAMAOBKMT2AMEN1 | |
| SCHEMBL14044868 | 0.74 | MEN1 (0.49) | TDP1MAOAMAOBKMT2AMEN1 | |
| SCHEMBL3131272 | 0.74 | TDP1 (0.47) | TDP1MAOAMAOBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122780-A9 | 2-PYRAZOLE ANILINES AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | THE KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-11-30 | — | — | WO | disclosed |
| WO-2023122780-A2 | 2-PYRAZOLE ANILINES AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | THE KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-06-29 | — | — | WO | disclosed |