Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 13/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 11/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | NOS2 | P35228 | 7/20 | 0.49 |
| ▸ | NOS1 | P29475 | 6/20 | 0.49 |
| ▸ | NOS3 | P29474 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4486154 | 0.80 | SLC6A4 (0.64) | SLC6A4SLC6A2CYP2D6SLC6A3KCNH2 | |
| SCHEMBL4477314 | 0.80 | SLC6A4 (0.56) | SLC6A4SLC6A2CYP2D6SLC6A3KCNH2 | |
| SCHEMBL4746288 | 0.80 | SLC6A4 (0.64) | SLC6A4SLC6A2CYP2D6SLC6A3KCNH2 | |
| SCHEMBL4485355 | 0.79 | SLC6A4 (0.63) | SLC6A4SLC6A2CYP2D6SLC6A3KCNH2 | |
| SCHEMBL5129536 | 0.74 | SLC6A4 (0.57) | SLC6A4SLC6A2CYP2D6SLC6A3KCNH2 | |
| SCHEMBL25326389 | 0.72 | SLC6A4 (0.56) | SLC6A4SLC6A2CYP2D6SLC6A3KCNH2 | |
| SCHEMBL4476276 | 0.72 | SLC6A4 (0.67) | SLC6A4SLC6A2CYP2D6SLC6A3KCNH2 | |
| SCHEMBL4483224 | 0.72 | SLC6A4 (0.57) | SLC6A4SLC6A2CYP2D6SLC6A3KCNH2 | |
| SCHEMBL5123815 | 0.71 | SLC6A4 (0.55) | SLC6A4SLC6A2CYP2D6SLC6A3KCNH2 | |
| SCHEMBL27641058 | 0.71 | SLC6A4 (0.55) | SLC6A4SLC6A2CYP2D6SLC6A3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122267-A2 | SMALL MOLECULE INHIBITORS OF MAMMALIAN SLC6A19 FUNCTION | JNANA THERAPEUTICS INC. (US) | 2023-06-29 | — | — | WO | disclosed |