Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 7/20 | 0.76 |
| ▸ | AURKA | O14965 | 1/20 | 0.65 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.65 |
| ▸ | ALK | Q9UM73 | 11/20 | 0.64 |
| ▸ | NEK2 | P51955 | 1/20 | 0.64 |
| ▸ | MET | P08581 | 4/20 | 0.53 |
| ▸ | INSR | P06213 | 2/20 | 0.53 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31173541 | 1.00 | AXL (0.76) | AXLAURKAAURKBALKNEK2 | |
| Formic Acid SCHEMBL31173436 | 0.96 | AXL (0.71) | AXLAURKAAURKBALKNEK2 | |
| SCHEMBL25838137 | 0.94 | AXL (0.75) | AXLAURKAAURKBALKNEK2 | |
| SCHEMBL31173443 | 0.92 | AXL (0.75) | AXLAURKAAURKBALKNEK2 | |
| SCHEMBL25837709 | 0.92 | AXL (0.75) | AXLAURKAAURKBALKNEK2 | |
| SCHEMBL31173432 | 0.91 | AXL (0.74) | AXLAURKAAURKBALKNEK2 | |
| SCHEMBL25837708 | 0.91 | AXL (0.74) | AXLAURKAAURKBALKNEK2 | |
| SCHEMBL25839123 | 0.89 | AXL (0.67) | AXLAURKAAURKBALKNEK2 | |
| SCHEMBL31173379 | 0.89 | AXL (0.67) | AXLAURKAAURKBALKNEK2 | |
| Formic Acid SCHEMBL31173418 | 0.88 | AXL (0.69) | AXLAURKAAURKBALKNEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023134582-A1 | PYRIMIDINE-2,4-DIAMINE DERIVATIVES AS WELL AS PREPARATION METHOD THEREFOR AND USE THEREOF | 上海立森印迹医药技术有限公司 | 2023-07-20 | — | — | WO | disclosed |