Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 6/20 | 0.67 |
| ▸ | AURKA | O14965 | 1/20 | 0.58 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.58 |
| ▸ | NEK2 | P51955 | 1/20 | 0.56 |
| ▸ | ALK | Q9UM73 | 12/20 | 0.54 |
| ▸ | INSR | P06213 | 4/20 | 0.52 |
| ▸ | MET | P08581 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31173379 | 1.00 | AXL (0.67) | AXLAURKAAURKBNEK2ALK | |
| SCHEMBL25837783 | 0.89 | AXL (0.76) | AXLAURKAAURKBNEK2ALK | |
| SCHEMBL31173541 | 0.89 | AXL (0.76) | AXLAURKAAURKBNEK2ALK | |
| Formic Acid SCHEMBL31173436 | 0.87 | AXL (0.71) | AXLAURKAAURKBNEK2ALK | |
| SCHEMBL25837708 | 0.86 | AXL (0.74) | AXLAURKAAURKBNEK2ALK | |
| SCHEMBL31173432 | 0.86 | AXL (0.74) | AXLAURKAAURKBNEK2ALK | |
| SCHEMBL30498941 | 0.86 | AXL (0.71) | AXLAURKAAURKBNEK2ALK | |
| SCHEMBL25838992 | 0.86 | AXL (0.71) | AXLAURKAAURKBNEK2ALK | |
| SCHEMBL31173443 | 0.85 | AXL (0.75) | AXLAURKAAURKBNEK2ALK | |
| SCHEMBL25837709 | 0.85 | AXL (0.75) | AXLAURKAAURKBNEK2ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023134582-A1 | PYRIMIDINE-2,4-DIAMINE DERIVATIVES AS WELL AS PREPARATION METHOD THEREFOR AND USE THEREOF | 上海立森印迹医药技术有限公司 | 2023-07-20 | — | — | WO | disclosed |