SCHEMBL25837836

SCHEMBL25837836

O=c1[nH]c2ccc3c(c4ccccc4n3-c3ccccc3)c2c2c1ccc1c2c2ccccc2n1-c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.46
KDM4E B2RXH2 2/20 0.46
ATM Q13315 1/20 0.46
JAK2 O60674 1/20 0.43
JAK3 P52333 1/20 0.43
ADORA3 P0DMS8 1/20 0.41
KMT2A Q03164 4/20 0.40
MEN1 O00255 3/20 0.40
LMNA P02545 2/20 0.40
MAT2A P31153 2/20 0.39
PDE7A Q13946 1/20 0.38
PDE7B Q9NP56 1/20 0.38
PARP1 P09874 2/20 0.38
MAPK8 P45983 2/20 0.37
ALDH1A1 P00352 2/20 0.37
HSD17B10 Q99714 2/20 0.37
TNKS O95271 1/20 0.37
CYP1A2 P05177 1/20 0.37
GPR3 P46089 1/20 0.37
BLM P54132 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25837156 0.86 L3MBTL1 (0.44) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL21375750 0.80 L3MBTL1 (0.49) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL29642039 0.80 L3MBTL1 (0.52) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL17254120 0.80 L3MBTL1 (0.52) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL25830610 0.79 KMT2A (0.37) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL19573604 0.79 L3MBTL1 (0.47) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL21185435 0.79 KDM4E (0.47) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL25830509 0.79 KDM4E (0.39) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL6569217 0.78 L3MBTL1 (0.74) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL25830678 0.78 KDM4E (0.53) L3MBTL1KDM4EATMJAK2JAK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023110742-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-06-22 WO disclosed