Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25837751 | 0.85 | PDK2 (0.38) | MAPK1 | |
| SCHEMBL25837884 | 0.83 | MAPK1 (0.33) | MAPK1DPP4DPP7 | |
| SCHEMBL25838478 | 0.82 | — | — | |
| SCHEMBL25837881 | 0.82 | MAPK1 (0.33) | MAPK1DPP4DPP7 | |
| SCHEMBL25837971 | 0.79 | CHRNB2 (0.36) | MAPK1HTR2AHTR2C | |
| SCHEMBL25838477 | 0.79 | PRMT5 (0.31) | — | |
| SCHEMBL25838492 | 0.79 | PRMT5 (0.30) | — | |
| SCHEMBL25837876 | 0.78 | PDK2 (0.37) | — | |
| SCHEMBL25838332 | 0.77 | GLRA1 (0.38) | — | |
| SCHEMBL25838323 | 0.77 | GFER (0.45) | MAPK1CFTRHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131122-A1 | FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2023-07-13 | — | — | WO | disclosed |