Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25832525 | 0.81 | CETP (0.36) | TP53RXFP1NPC1RAB9ACEPT1 | |
| SCHEMBL25827001 | 0.76 | POLB (0.48) | NAMPTNPC1RAB9AMAPTKDM4E | |
| SCHEMBL25827803 | 0.75 | PKN1 (0.44) | TP53MAPTKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL24006292 | 0.75 | MAPKAPK2 (0.47) | TP53RXFP1NAMPTNPC1RAB9A | |
| SCHEMBL24003896 | 0.75 | MAPKAPK2 (0.47) | TP53RXFP1NAMPTNPC1RAB9A | |
| SCHEMBL25853246 | 0.72 | NPC1 (0.40) | TP53RXFP1NAMPTNPC1RAB9A | |
| SCHEMBL25490539 | 0.71 | POLB (0.43) | NAMPTMAPTKDM4EPOLBPPARG | |
| SCHEMBL23999737 | 0.70 | F10 (0.41) | NAMPTRAB9AMAPTKDM4EPOLB | |
| SCHEMBL25821785 | 0.69 | MAPKAPK2 (0.48) | TP53NPC1RAB9ACASP3SENP8 | |
| SCHEMBL24006295 | 0.69 | MAPKAPK2 (0.46) | TP53RXFP1CEPT1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | TP53 435/4885RXFP1 4004/4885NAMPT 1361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.