Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKN1 | Q16512 | 1/20 | 0.44 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 6/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 6/20 | 0.37 |
| ▸ | CSNK1G2 | P78368 | 6/20 | 0.37 |
| ▸ | GSK3B | P49841 | 5/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25838393 | 0.81 | KIT (0.31) | PKN1PKN2 | |
| SCHEMBL25827001 | 0.76 | POLB (0.48) | ALDH1A1KDM4EGAAMAPTSMN1; SMN2 | |
| SCHEMBL25838198 | 0.75 | TP53 (0.41) | ALDH1A1HPGDKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL24006229 | 0.74 | KDR (0.52) | PKN1PKN2CSNK1A1CSNK1DCSNK1G2 | |
| SCHEMBL25832525 | 0.72 | CETP (0.36) | MAPTPOLBTP53 | |
| SCHEMBL23999737 | 0.72 | F10 (0.41) | ALDH1A1KDM4EMAPTPOLBKMT2A | |
| SCHEMBL25490539 | 0.71 | POLB (0.43) | ALDH1A1HPGDKDM4EMAPTPOLB | |
| SCHEMBL23999436 | 0.67 | KDR (0.59) | PKN1PKN2CSNK1A1CSNK1DCSNK1G2 | |
| SCHEMBL23999350 | 0.67 | KDR (0.59) | PKN1PKN2CSNK1A1CSNK1DCSNK1G2 | |
| SCHEMBL30287670 | 0.66 | KDR (0.58) | PKN1PKN2CSNK1A1CSNK1DCSNK1G2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | PKN1 707/4885PKN2 578/4885ALDH1A1 3871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.