SCHEMBL25838278

SCHEMBL25838278

Cc1cc(N2CCc3cc(C(C)C)cc([C@@H]4CCCN4)c3C2)ccn1

nearest known ligand 0.46

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TLR9 Q9NR96 2/20 0.34
TLR8 Q9NR97 2/20 0.34
TLR7 Q9NYK1 2/20 0.34
EED O75530 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25838309 0.88 TAAR1 (0.30)
SCHEMBL25838310 0.78 MEN1 (0.35) EED
SCHEMBL25297241 0.78 PIK3CG (0.35)
SCHEMBL30491262 0.78 PIK3CG (0.35)
SCHEMBL25254964 0.78 PIK3CG (0.35)
SCHEMBL25838311 0.77 CHRM4 (0.35) EED
Formic Acid SCHEMBL27125779 0.74 PIK3CG (0.35)
Formic Acid SCHEMBL27125780 0.74 PIK3CG (0.35)
SCHEMBL30491458 0.73 EED (0.40) EED
SCHEMBL30491189 0.73 AOC3 (0.32) EED

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023131122-A1 FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF 劲方医药科技(上海)有限公司 2023-07-13 WO disclosed