Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25165313 | 0.86 | HDAC6 (0.33) | MEN1KMT2AHDAC6DPP4HDAC1 | |
| SCHEMBL6935567 | 0.85 | L3MBTL1 (0.32) | MEN1KMT2AHDAC6DPP4HDAC1 | |
| SCHEMBL21403608 | 0.85 | L3MBTL1 (0.32) | MEN1KMT2AHDAC6DPP4HDAC1 | |
| SCHEMBL25165441 | 0.85 | HDAC6 (0.33) | MEN1KMT2AHDAC6DPP4HDAC1 | |
| SCHEMBL10634002 | 0.85 | L3MBTL1 (0.32) | MEN1KMT2AHDAC6DPP4HDAC1 | |
| SCHEMBL3247270 | 0.84 | HDAC6 (0.35) | HDAC6HDAC1HDAC2CA1CA2 | |
| SCHEMBL21403646 | 0.83 | HDAC6 (0.31) | MEN1KMT2AHDAC6DPP4 | |
| SCHEMBL22539779 | 0.83 | CA14 (0.33) | MEN1KMT2AHDAC6DPP4NPSR1 | |
| SCHEMBL3946398 | 0.83 | MEN1 (0.33) | MEN1KMT2AHDAC6DPP4NPSR1 | |
| SCHEMBL2720340 | 0.83 | HDAC6 (0.33) | HDAC6DPP4HDAC1HDAC2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122780-A9 | 2-PYRAZOLE ANILINES AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | THE KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-11-30 | — | — | WO | disclosed |
| WO-2023122780-A2 | 2-PYRAZOLE ANILINES AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | THE KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-06-29 | — | — | WO | disclosed |