Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | PHGDH | O43175 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3074321 | 0.97 | MGLL (0.42) | MGLLPHGDHALDH1A1TP53CYP3A4 | |
| SCHEMBL11570146 | 0.82 | MGLL (0.36) | MGLLPHGDHALDH1A1TP53CYP3A4 | |
| SCHEMBL2807856 | 0.77 | MGLL (0.40) | MGLLPHGDHALDH1A1TP53CYP3A4 | |
| SCHEMBL27685214 | 0.77 | — | — | |
| SCHEMBL7741300 | 0.77 | MGLL (0.40) | MGLLPHGDHALDH1A1TP53CYP3A4 | |
| SCHEMBL27686549 | 0.77 | — | — | |
| SCHEMBL3081950 | 0.77 | MGLL (0.37) | MGLLPHGDHFAAH | |
| SCHEMBL28515771 | 0.75 | MGLL (0.33) | MGLLPHGDH | |
| SCHEMBL11444353 | 0.75 | MGLL (0.39) | MGLLPHGDHALDH1A1TP53CYP3A4 | |
| SCHEMBL27565787 | 0.75 | MGLL (0.39) | MGLLPHGDHALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809726-B1 | USE OF 1,3-DITHIOLANE-2-THIONE ADDITIVES FOR LUBRICANTS | LANXESS SOLUTIONS US INC (US) | 2019-08-28 | — | — | EP | disclosed |
| US-8048832-B2 | 1,3 dithiolane-2-thione additives for lubricants and fuels | CHEMTURA CORPORATION (US) | 2011-11-01 | — | — | US | disclosed |
| US-20090181870-A1 | 1,3 DITHIOLANE-2-THIONE ADDITIVES FOR LUBRICANTS AND FUELS | CHEMTURA CORPORATION (US) | 2009-07-16 | — | — | US | disclosed |
| US-7541319-B2 | 1,3-dithiolane-2-thione additives for lubricants and fuels | CHEMTURA CORPORATION (US) | 2009-06-02 | — | — | US | disclosed |
| EP-1809726-A2 | 1,3-DITHIOLANE-2-THIONE ADDITIVES FOR LUBRICANTS AND FUELS | CHEMTURA CORPORATION (US) | 2007-07-25 | — | — | EP | disclosed |
| WO-2006047011-A2 | 1,3-DITHIOLANE-2-THIONE ADDITIVES FOR LUBRICANTS AND FUELS | CHEMTURA CORPORATION (US) | 2006-05-04 | — | — | WO | disclosed |
| US-20060089273-A1 | 1,3-Dithiolane-2-thione additives for lubricants and fuels | LANXESS SOLUTIONS US INC. | 2006-04-27 | — | — | US | disclosed |