Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30510071 | 0.78 | MEN1 (0.53) | MEN1KMT2AKDM4EHPGDALDH1A1 | |
| SCHEMBL25832669 | 0.78 | MEN1 (0.53) | MEN1KMT2AKDM4EHPGDALDH1A1 | |
| SCHEMBL989177 | 0.78 | CA12 (0.42) | MEN1KMT2ARAB9AALDH1A1NPC1 | |
| Hydrochloric Acid SCHEMBL25378772 | 0.77 | MEN1 (0.52) | MEN1KMT2AKDM4EHPGDALDH1A1 | |
| Water SCHEMBL28192673 | 0.76 | CA12 (0.41) | MEN1KMT2ARAB9AKDM4EHPGD | |
| Hydrochloric Acid SCHEMBL7809921 | 0.76 | CA12 (0.41) | MEN1KMT2ARAB9AALDH1A1NPC1 | |
| SCHEMBL25256189 | 0.72 | SCN4A (0.54) | MEN1KMT2ARAB9AKDM4EHPGD | |
| SCHEMBL1385301 | 0.70 | SCN4A (0.51) | MEN1KMT2ARAB9AKDM4EHPGD | |
| SCHEMBL3364919 | 0.69 | CYP1A2 (0.42) | MEN1KMT2ARAB9AALDH1A1MAPK1 | |
| SCHEMBL16766999 | 0.68 | LMNA (0.36) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122780-A9 | 2-PYRAZOLE ANILINES AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | THE KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-11-30 | — | — | WO | disclosed |
| WO-2023122780-A2 | 2-PYRAZOLE ANILINES AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | THE KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-06-29 | — | — | WO | disclosed |