Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | TYMS | P04818 | 7/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30517063 | 1.00 | POLB (0.58) | POLBMEN1KMT2ATYMSCYP1B1 | |
| SCHEMBL29362967 | 0.85 | TYMS (0.61) | POLBMEN1KMT2ATYMSCYP1B1 | |
| SCHEMBL320954 | 0.85 | TYMS (0.61) | POLBMEN1KMT2ATYMSCYP1B1 | |
| SCHEMBL18021867 | 0.80 | KDM4E (0.56) | POLBMEN1KMT2ACYP1B1ALDH1A1 | |
| SCHEMBL29769022 | 0.80 | KDM4E (0.56) | POLBMEN1KMT2ACYP1B1ALDH1A1 | |
| SCHEMBL200283 | 0.80 | TYMS (0.47) | POLBMEN1KMT2ATYMSCYP1B1 | |
| SCHEMBL18021873 | 0.76 | KDM4E (0.56) | POLBMEN1KMT2ATYMSCYP1B1 | |
| SCHEMBL30496683 | 0.76 | KDM4E (0.56) | POLBMEN1KMT2ATYMSCYP1B1 | |
| SCHEMBL17727980 | 0.76 | AHR (0.46) | POLBMEN1KMT2ACYP1B1ALDH1A1 | |
| SCHEMBL24277323 | 0.75 | AHR (0.47) | CYP1B1KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125877-A1 | TRICYCLIC DERIVATIVE INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 上海翰森生物医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |