SCHEMBL29362967

SCHEMBL29362967

O=C1OC(=O)c2ccc(Br)c3cccc1c23

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TYMS P04818 3/20 0.61
CYP1B1 Q16678 14/20 0.56
CYP1A2 P05177 1/20 0.51
ALDH1A1 P00352 2/20 0.51
POLB P06746 2/20 0.51
RXFP1 Q9HBX9 1/20 0.51
KDM4E B2RXH2 1/20 0.47
MEN1 O00255 1/20 0.47
NPC1 O15118 1/20 0.47
LMNA P02545 1/20 0.47
MAPT P10636 1/20 0.47
PABPC1 P11940 1/20 0.47
KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL320954 1.00 TYMS (0.61) TYMSCYP1B1CYP1A2ALDH1A1POLB
SCHEMBL200283 0.87 TYMS (0.47) TYMSCYP1B1CYP1A2ALDH1A1POLB
SCHEMBL77179 0.85 CYP1B1 (0.61) CYP1B1CYP1A2ALDH1A1POLBRXFP1
SCHEMBL29583035 0.85 CYP1B1 (0.61) CYP1B1CYP1A2ALDH1A1POLBRXFP1
SCHEMBL30517063 0.85 POLB (0.58) TYMSCYP1B1CYP1A2ALDH1A1POLB
SCHEMBL25839221 0.85 POLB (0.58) TYMSCYP1B1CYP1A2ALDH1A1POLB
SCHEMBL10267341 0.83 TYMS (0.70) TYMSCYP1A2ALDH1A1POLBKDM4E
SCHEMBL10350796 0.80 PABPC1 (0.58) CYP1B1CYP1A2ALDH1A1POLBRXFP1
SCHEMBL1356074 0.79 TYMS (0.43) TYMSCYP1B1CYP1A2ALDH1A1POLB
SCHEMBL663504 0.79 CYP1A2 (0.63) CYP1B1CYP1A2ALDH1A1POLBRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 194 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010901-A D-A-D' asymmetric decoupling organic X-ray scintillator, and synthetic method and application thereof 大连理工大学 2026-05-12 CN claimed
CN-120081786-A Schiff base optical switch material, preparation method thereof and static three-dimensional display system 安徽省东超科技有限公司 2025-06-03 CN claimed
CN-120058606-A Enamine N-oxide containing naphthalimide fluorophore, preparation method thereof and application thereof as Fe2+Use in fluorescent probes 杭州师范大学 2025-05-30 CN claimed
CN-119823290-A Cellulose acetate-based 1, 8-naphthalimide fluorescent probe for detecting hydrazine and preparation method and application thereof 南京林业大学 2025-04-15 CN claimed
CN-119552117-A AIE type fluorescent probe with tumor targeting and preparation and application thereof 西安电子科技大学 2025-03-04 CN claimed
CN-119529195-A Naphthalimide-based polyacrylate polymer fluorescent probe, preparation method and application 山东博伦特药业有限公司 2025-02-28 CN claimed
CN-119529199-A Dynamic covalent cross-linking material based on thermoplastic polymer and preparation method and application thereof 北京化工大学 2025-02-28 CN claimed
CN-116751208-B Ratio type fluorescent probe for detecting ClO-based on pyranoquinoline 郑州大学 2025-02-14 CN claimed
CN-116370645-B Endoplasmic reticulum targeted fluorescent nano-carrier, preparation method and application thereof 齐鲁工业大学(山东省科学院) 2025-01-14 CN claimed
CN-116332846-B Be used for detecting H2Fluorescent probe of S gas signal molecule and preparation method and application thereof 湖北南博生物工程有限公司 2024-12-10 CN claimed
CN-114436961-B Acid response fluorescent small molecule, preparation method and application thereof 吴江市汉塔纺织整理有限公司 2023-09-15 CN claimed
CN-116606334-A Fluorescent dye, preparation method thereof and prepared fluorescent probe 北京兴德通医药科技股份有限公司 2023-08-18 CN claimed
CN-114702447-B Naphthalimide derivative and preparation method and application thereof 苏州大学 2023-07-11 CN claimed
CN-116332846-A Be used for detecting H 2 Fluorescent probe of S gas signal molecule and preparation method and application thereof 湖北南博生物工程有限公司 2023-06-27 CN claimed
CN-116332847-A AIE active naphthalimide compound containing methylthio and preparation method and application thereof 上海工程技术大学 2023-06-27 CN claimed
CN-113307771-B Fluorescent dye with large Stokes displacement and preparation method thereof 西北大学 2023-06-09 CN claimed
CN-116102681-A Preparation method of amphoteric wet finishing material with retanning, fatliquoring and dyeing functions 陕西科技大学 2023-05-12 CN claimed
CN-114507214-B Fluorescent compound, fluorescent probe, fluorescent sensing film, and preparation methods and applications thereof 河北师范大学 2023-04-28 CN claimed
CN-114605383-B Red light delayed fluorescent material and exciplex acceptor material based on naphthalene anhydride 电子科技大学 2023-04-25 CN claimed
CN-112662313-B Preparation method of polyphosphazene modified polyesterimide water-based heat-conducting coating 安徽喜宝高分子材料有限公司 2022-03-08 CN claimed