Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.46 |
| ▸ | IKBKB | O14920 | 2/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.41 |
| ▸ | NEK1 | Q96PY6 | 2/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CHI3L1 | P36222 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28314924 | 0.85 | HRH3 (0.53) | HRH3LMNAMAP4K4KCNH2CHI3L1 | |
| SCHEMBL24112880 | 0.76 | LMNA (0.45) | LMNA | |
| SCHEMBL25839613 | 0.76 | LMNA (0.45) | LMNA | |
| SCHEMBL25839614 | 0.76 | LMNA (0.45) | LMNA | |
| SCHEMBL12090211 | 0.75 | MAP4K4 (0.49) | HRH3IKBKBPRKAG1PRKAA1NEK1 | |
| SCHEMBL8302404 | 0.73 | KDM4E (0.50) | HRH3IKBKBPRKAG1PRKAA1NEK1 | |
| SCHEMBL25839616 | 0.73 | CYP19A1 (0.45) | HRH3 | |
| SCHEMBL12090380 | 0.73 | KCNH2 (0.53) | HRH3IKBKBPRKAG1PRKAA1NEK1 | |
| SCHEMBL28214356 | 0.73 | KDM4E (0.41) | HRH3IKBKBPRKAG1PRKAA1NEK1 | |
| SCHEMBL1515445 | 0.73 | SMN1; SMN2 (0.48) | HRH3MAP4K4KDM4ESMN1; SMN2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125825-A1 | ANTICORONVIRAL COMPOUNDS AND COMPOSITIONS AND USES THEREOF | SHANGHAI CUREGENE PHARMACEUTICAL CO., LTD. (CN) | 2023-07-06 | — | — | WO | disclosed |