Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 14/20 | 0.79 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.78 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.78 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29395154 | 0.88 | P2RX4 (1.00) | P2RX4P2RX1P2RX3CTRB1NPSR1 | |
| SCHEMBL26478548 | 0.88 | P2RX4 (1.00) | P2RX4P2RX1P2RX3CTRB1NPSR1 | |
| SCHEMBL31722365 | 0.88 | P2RX4 (1.00) | P2RX4P2RX1P2RX3CTRB1NPSR1 | |
| SCHEMBL25840356 | 0.78 | BCHE (0.63) | P2RX4P2RX1P2RX3MAPTMEN1 | |
| SCHEMBL19773283 | 0.76 | P2RX4 (0.54) | P2RX4P2RX1P2RX3CTRB1NPSR1 | |
| SCHEMBL22808207 | 0.74 | P2RX4 (0.57) | P2RX4P2RX1P2RX3MAPTSMN1; SMN2 | |
| SCHEMBL25649049 | 0.72 | P2RX4 (0.62) | P2RX4P2RX1P2RX3CTRB1NPSR1 | |
| SCHEMBL22808203 | 0.71 | TP53 (0.61) | P2RX4P2RX1P2RX3MAPTSMN1; SMN2 | |
| SCHEMBL22493214 | 0.71 | P2RX4 (0.65) | P2RX4P2RX1P2RX3CTRB1NPSR1 | |
| SCHEMBL24428006 | 0.70 | P2RX4 (0.54) | P2RX4P2RX1P2RX3MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023117836-A1 | ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-06-29 | — | — | WO | disclosed |