SCHEMBL24428006

SCHEMBL24428006

O=C(OCc1ccccc1)c1ccc2c(c1)Oc1cccc3c1N2c1ccccc1O3

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RX4 Q99571 5/20 0.54
P2RX1 P51575 1/20 0.54
P2RX3 P56373 1/20 0.54
LMNA P02545 4/20 0.48
TDP1 Q9NUW8 4/20 0.48
KMT2A Q03164 2/20 0.48
SLC6A2 P23975 1/20 0.48
SLC6A3 Q01959 1/20 0.48
ALDH1A1 P00352 6/20 0.46
RAB9A P51151 5/20 0.46
SMN1; SMN2 Q16637 4/20 0.46
NPC1 O15118 4/20 0.46
MAPT P10636 3/20 0.46
KDM4E B2RXH2 1/20 0.46
HTT P42858 1/20 0.45
HPGD P15428 1/20 0.43
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
SRD5A1 P18405 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21323158 0.73 TSHR (0.68) LMNATDP1KMT2ASLC6A2SLC6A3
SCHEMBL312910 0.73 TDP1 (0.81) LMNATDP1KMT2ASLC6A2SLC6A3
SCHEMBL26478548 0.71 P2RX4 (1.00) P2RX4P2RX1P2RX3KMT2AALDH1A1
SCHEMBL29395154 0.71 P2RX4 (1.00) P2RX4P2RX1P2RX3KMT2AALDH1A1
SCHEMBL31722365 0.71 P2RX4 (1.00) P2RX4P2RX1P2RX3KMT2AALDH1A1
SCHEMBL312287 0.71 KMT2A (0.92) LMNATDP1KMT2ASLC6A2SLC6A3
SCHEMBL6002245 0.70 KMT2A (0.70) LMNATDP1KMT2ASLC6A2SLC6A3
SCHEMBL25840355 0.70 P2RX4 (0.79) P2RX4P2RX1P2RX3KMT2ARAB9A
SCHEMBL6282770 0.69 KMT2A (0.81) LMNATDP1KMT2ASLC6A2SLC6A3
SCHEMBL5834916 0.69 ALDH1A1 (0.68) LMNATDP1KMT2ASLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3596066-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2022-05-18 EP disclosed