Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13082726 | 0.80 | KDM4E (0.36) | KDM4EGAATSHROPRM1OPRD1 | |
| SCHEMBL3477253 | 0.76 | KDM4E (0.46) | KDM4EGAATSHROPRM1OPRD1 | |
| SCHEMBL92656 | 0.76 | GAA (0.34) | KDM4EGAATSHROPRM1OPRD1 | |
| SCHEMBL10179741 | 0.75 | KDM4E (0.36) | KDM4EGAATSHROPRM1OPRD1 | |
| SCHEMBL6922492 | 0.74 | GAA (0.38) | KDM4EGAATSHROPRM1OPRD1 | |
| SCHEMBL15806842 | 0.73 | OPRM1 (0.33) | KDM4EGAATSHROPRM1OPRD1 | |
| SCHEMBL21651974 | 0.73 | KDM4E (0.33) | KDM4EGAATSHR | |
| SCHEMBL22254744 | 0.73 | CYP2D6 (0.34) | KDM4EGAATSHR | |
| SCHEMBL92634 | 0.73 | KDM4E (0.33) | KDM4EGAATSHR | |
| SCHEMBL20008009 | 0.73 | KDM4E (0.33) | KDM4EGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116763-A1 | PYRIDAZINE COMPOUND, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 上海优理惠生医药有限公司 | 2023-06-29 | — | — | WO | disclosed |