Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 16/20 | 0.68 |
| ▸ | MAOA | P21397 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | MIF | P14174 | 1/20 | 0.65 |
| ▸ | ACHE | P22303 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8461421 | 0.84 | MIF (0.67) | MAOBMAOATDP1MEN1KMT2A | |
| SCHEMBL8461418 | 0.84 | MIF (0.67) | MAOBMAOATDP1MEN1KMT2A | |
| SCHEMBL5724935 | 0.83 | MIF (0.76) | MAOBMAOATDP1MEN1KMT2A | |
| SCHEMBL8546817 | 0.83 | MIF (0.72) | MAOBTDP1MEN1KMT2AMIF | |
| SCHEMBL6956078 | 0.83 | MIF (0.72) | MAOBTDP1MEN1KMT2AMIF | |
| SCHEMBL31179771 | 0.81 | MAOB (1.00) | MAOBMAOATDP1MEN1KMT2A | |
| SCHEMBL29595747 | 0.81 | MAOB (1.00) | MAOBMAOATDP1MEN1KMT2A | |
| SCHEMBL979717 | 0.81 | MAOB (1.00) | MAOBMAOATDP1MEN1KMT2A | |
| SCHEMBL979718 | 0.81 | MAOB (1.00) | MAOBMAOATDP1MEN1KMT2A | |
| SCHEMBL31237283 | 0.77 | DYRK1A (0.62) | TDP1MEN1KMT2AMIFALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215522-A1 | DERIVATIVES OF 4-CHROMONE AS INHIBITORS OF THE RDRP POLYMERASE OF SARS-COV-2 VIRUS AND METHOD FOR THE PREPARATION THEREOF | Fondazione Istituto Italiano di Tecnologia (IT) | 2023-07-26 | — | — | EP | disclosed |